Drug-Drug Interaction (DDI) Alert

A Drug-Drug Interaction alert message appears when a prescribed drug has the potential to cause significant interactions with other drugs in the patient's Active Medications list.

There are three Drug-Drug Alert severity levels:

• ​Major Drug Interaction — The effects may result in death, hospitalization, permanent injury, or therapeutic failure.
• Moderate Drug Interaction — Medical intervention is needed to treat effects; effects do not meet criteria for Major.
• Minor Drug Interaction — The effects would be considered tolerable in most cases - no need for medical intervention.

Based on your Drug-Drug Alert notification settings (under prescription preferences), you have the following choices when an alert appears:

• Select an Override Reason and proceed with the prescription.
• Override the alert and proceed with the prescription​ without selecting an override reason.
• Cancel the prescription.

This Presciption: Name of drug you are prescribing. Existing Prescription: Drug in the patient's Active Medications list that interacts with the drug being prescribed. DDI Severity: Severity level of interaction. Details: Provides information about the drug interaction. Override Reason: Allows you to override the alert by selecting the appropriate check box(es). "Don't show this alert again": Check this box to turn off future alerts for this Drug-Drug Interaction. Cancel Rx: Cancels the prescription in progress. Continue Rx: Based on your Drug-Drug Interaction settings, click to continue prescribing the drug with or without selecting an Override Reason.